Unfortunately Chuck's past lucrative secular career is often referred to. However his career ended abruptly after he had become the chairman of a small, publicly owned development company which made a multi-billion dollar agreement with the Soviet Union to supply personal computers to 143,000 schools. Unfortunately, unforeseen circumstances arose and the venture failed. The Misslers lost everything, including their home, automobiles and insurance.

Chuck's good friend, Hal Lindsey, encouraged Chuck to take up his number one passion which was to teach the Bible, and devote himself to full-time ministry. Chuck and Nancy established Koinonia House in 1973 and after a terrible earthquake demolished their home in Big Bear, California in 1992, Chuck and Nancy moved Koinonia House to Coeur d'Alene, Idaho. "A small ministry that casts a large shadow" as he puts it, Chuck went on to produce many briefings and commentaries that have been played on radio stations and TV worldwide. Chuck lived out his final years in a small house at K-House's Southern base, The River Lodge in rural New Zealand. (See also Chuck's Biography)